RCAN1 anticorps (Middle Region)
Aperçu rapide pour RCAN1 anticorps (Middle Region) (ABIN358860)
Antigène
Voir toutes RCAN1 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- Middle Region
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Specificité
- This antibody reacts to DSCR1.
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Purification
- Protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS
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Immunogène
- This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the center region of human DSCR1.
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Isotype
- Ig Fraction
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Indications d'application
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ELISA: 1/1,000. Western blotting: 1/100 - 1/500.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 0.25 mg/mL
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Buffer
- PBS with 0.09 % (W/V) sodium azide
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Conseil sur la manipulation
- Avoid repeated freezing and thawing.
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Stock
- 4 °C/-20 °C
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Stockage commentaire
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.
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- RCAN1 (Regulator of Calcineurin 1 (RCAN1))
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Autre désignation
- Calcipressin-1
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Sujet
- DSCR1 (calcipressin 1) interacts with calcineurin A and inhibits calcineurin-dependent signaling pathways, possibly affecting central nervous system development. Thr gene for this protein is located in the minimal candidate region for the Down syndrome phenotype, and is overexpressed in the brain of Down syndrome fetuses. Chronic overexpression of this gene may lead to neurofibrillary tangles such as those associated with Alzheimer disease.Synonyms: ADAPT78, CSP1, DSC1, DSCR1, Down syndrome critical region protein 1, Myocyte-enriched calcineurin-interacting protein 1, RCAN1, Regulator of calcineurin 1
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ID gène
- 1827, 9606
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UniProt
- P53805
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Pathways
- Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development
Antigène
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